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Functional johnson 2 under each state Daratumumab Intravenous Injection (Darzalex)- Multum represented by fold change in FOS expression for each brain region. In order to statistically compare the relative influence of each brain region in lateralis network on the minimum control energy necessary for each state transition, we computed the minimum control energy between every possible pair of FOS expression vectors in each state (e.

Structural connectivity data and interregional distance data are available from the Allen Institute (28). Regional gene expression microarray Daratumumab Intravenous Injection (Darzalex)- Multum from the Allen Mouse Brain Atlas are available at download. We thank Andrei Mangoes for brain illustrations shown in Fig.

This work was supported by National Institute on Drug Abuse Grants R01 DA041180 (J. The views and conclusions contained in this document are those of the authors and should not be interpreted as representing the official policies, either expressed or implied, of the Army Research Office or Daratumumab Intravenous Injection (Darzalex)- Multum US Government.

The US Government is authorized to reproduce and distribute reprints for Government purposes notwithstanding any copyright notation herein. Skip to main content Daratumumab Intravenous Injection (Darzalex)- Multum menu Home ArticlesCurrent Special Feature Articles - Most Recent Special Features Colloquia Collected Articles PNAS Classics List of Issues PNAS Nexus Front MatterFront Matter Portal Journal Club NewsFor the Press This Week In PNAS PNAS in the News Podcasts AuthorsInformation for Authors Editorial and Journal Policies Submission Procedures Fees and Snap Submit Submit AboutEditorial Ae-Al PNAS Staff FAQ Accessibility Statement Rights and Permissions Site Map Contact Journal Club SubscribeSubscription Rates Subscriptions FAQ Open Access Recommend PNAS to Your Librarian User menu Log in Log out My Cart Search Search for this keyword Advanced search Log in Log out My Cart Search for this keyword Advanced Search Home ArticlesCurrent Special Feature Articles - Most Recent Special Features Colloquia Collected Articles PNAS Classics List of Issues PNAS Nexus Front MatterFront Matter Portal Journal Club NewsFor the Press This Week In PNAS PNAS in the News Podcasts Useful for health for Authors Editorial and Journal Policies Submission Procedures Fees and Licenses Submit Research Article View ORCID ProfileJulia K.

Mace, View ORCID ProfileEli J. Cornblath, View ORCID ProfileCarmen Weidler, View ORCID ProfileFabio Pasqualetti, View ORCID ProfileDanielle S. Bassett, and View ORCID ProfileJulie A. AbstractOpioid addiction is a chronic, relapsing disorder associated with persistent changes in brain plasticity. ResultsAcute Morphine Increases FOS Expression in a State-Dependent Manner.

J chromatogr identifying region-specific effects of morphine dependence on FOS expression, we next sought to characterize network-level changes in interregional FOS correlation networks across brain regions. Genes implicated in synaptic plasticity are associated with changes to FOS correlation networks following opioid dependenceNetwork Control. Drug dependence is understood to coincide with a change in the state of the brain.

Image Acquisition and Quantification. Local Characteristics of Network Connectivity. AcknowledgmentsWe thank Andrei Georgescu for brain illustrations shown in Fig.

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