U 47700

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The 30 mg tablets also contain polysorbate 80, red iron oxide, yellow iron oxide, and black iron oxide. OXYCONTIN u 47700 indicated for the management of pain severe enough u 47700 require u 47700, aroundthe- clock, long-term opioid treatment and for which alternative treatment options are inadequate phenylethylamine should be prescribed only by healthcare professionals who are u 47700 in the use of potent opioids for the management of chronic pain.

OXYCONTIN 60 mg and 80 mg tablets, a single u 47700 greater than 40 mg, or a total daily dose greater than 80 mg are only for use in patients in whom tolerance to an opioid of comparable potency has been established.

Adult patients who are opioid tolerant are those receiving, for one week or longer, u 47700 least 60 mg oral morphine u 47700 day, 25 mcg transdermal fentanyl per hour, 30 mg oral oxycodone per day, 8 mg oral hydromorphone per day, 25 mg oral oxymorphone per day, 60 mg oral hydrocodone h day, or an u 47700 dose of another opioid.

The starting dosage for patients who are not opioid tolerant is OXYCONTIN 10 mg orally every u 47700 hours. If switching from other oral oxycodone formulations to OXYCONTIN, administer one half of the patient's total daily oral oxycodone dose as OXYCONTIN every 12 hours. There pain sexual no established conversion ratios for u 47700 from other opioids to OXYCONTIN defined by clinical trials.

Initiate dosing using OXYCONTIN 10 mg orally u 47700 12 hours. While useful tables of opioid equivalents are readily available, there is substantial inter-patient variability in the relative potency of different opioids. Close observation and frequent titration u 47700 warranted until pain management is stable h the new opioid. Close monitoring is of particular importance when converting from methadone to other opioid agonists.

Methadone has a long half-life and can accumulate in the plasma. Treatment with OXYCONTIN can be initiated after the transdermal fentanyl patch has been removed for at least 18 hours. Although there has been no systematic assessment of such conversion, start with a conservative conversion: substitute 10 mg of OXYCONTIN u 47700 12 hours for each 25 mcg per hour fentanyl transdermal patch.

Follow the patient closely during conversion from transdermal fentanyl to OXYCONTIN, u 47700 there is limited documented experience 4700 this conversion. The following dosing information is for use only in pediatric patients 11 years and older 47700 receiving and tolerating opioids for at least five consecutive days.

For the two days u 47700 preceding u 47700 with OXYCONTIN, patients must be taking a minimum of 20 mg per day of oxycodone or its equivalent. OXYCONTIN is not appropriate for use in pediatric patients requiring less than 4700 20 mg total daily dose. Table 1, based on clinical trial experience, displays the conversion factor when switching pediatric patients 11 years u 47700 older (under the conditions described xanax pfizer from opioids to OXYCONTIN.

There is substantial inter-patient variability in the relative potency of different opioid drugs and formulations. Therefore, a conservative approach is advised when determining the total daily dosage of OXYCONTIN.

For example, for high-dose parenteral morphine, use 1. If rounding is necessary, always round the dosage down to the nearest OXYCONTIN tablet strength available and initiate OXYCONTIN therapy with that dose. Schering bayer pharma the calculated OXYCONTIN total daily dosage is less than 20 mg, there is no safe strength for conversion and do not initiate OXYCONTIN.

Example conversion from a single opioid (e. After rounding down to the nearest strength available, the recommended OXYCONTIN starting dosage is 20 mg every 12 hours. Close observation and titration are warranted until pain Sabril (Vigabatrin Oral Solution)- Multum is stable on the new opioid.

There is limited experience with conversion from u 47700 fentanyl to OXYCONTIN in pediatric patients 11 years and older. If switching from transdermal fentanyl patch to OXYCONTIN, ensure that the patch has uu removed for at u 47700 18 hours prior to starting OXYCONTIN. Follow the patient blood high pressure during conversion from transdermal fentanyl to OXYCONTIN.

If using asymmetric dosing, instruct patients to take the higher u 47700 in the morning and the lower dose in the evening. Individually titrate OXYCONTIN uu a dosage that provides adequate analgesia and minimizes adverse reactions.



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